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ABOUT HD &
HD CHOREA

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Huntington’s disease (HD) is a hereditary disorder that causes nerve cells in the brain to gradually break down.

Over time, this damage causes symptoms that can disrupt everyday life physically, mentally, and emotionally.

Stages of HD chorea

EARLY

A gradual increase in uncontrollable movements may impact daily function

MIDDLE

Chorea may become worse, leading to increased difficulty with muscle control

LATE

Chorea may become severe or stabilize; people may also experience muscle stiffness and the inability to walk or speak


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CHOREA (UNCONTROLLABLE MOVEMENTS) IS THE DEFINING SYMPTOM OF HD, AND CAN BE ONE OF THE MOST IMPACTFUL*

* In an HDSA survey, HD patients and caregivers were asked to identify HD symptoms that had the biggest impact on daily life. Of 2591 respondents, 30% of caregivers and 17% of HD patients reported chorea as the most impactful.

HD chorea is progressive and some of the areas it affects can include:

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Finger and hand coordination:
loss of muscle control can lead to problems with manual dexterity

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Walking:
balance issues can lead to falls

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Mouth movements:
uncontrollable movements can cause difficulty with talking and chewing

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Swallowing:
swallowing difficulties may lead to choking


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If you notice these symptoms in yourself or a loved one, you should start a conversation with your healthcare provider—even if the symptoms are mild.

Over time, HD chorea may worsen, which could make daily life more difficult for those living with HD and their caregivers.

HD CHOREA CAN MAKE DAILY ACTIVITIES
MORE CHALLENGING, SUCH AS:

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Bathing

Eating or swallowing

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Dressing

Speaking

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THERE IS NOT YET A CURE OR TREATMENT TO DELAY HD PROGRESSION, BUT THERE ARE MEDICATIONS THAT CAN HELP CONTROL HD CHOREA

Don’t wait until your or your loved one’s movements have started affecting daily living to begin a conversation with your healthcare provider about appropriately managing HD chorea.

Download the INGREZZA Patient Brochure for HD chorea

Learn about Huntington’s Disease (HD) and HD chorea, how INGREZZA works, and the difference it can make in treating uncontrollable movements from HD chorea.

INGREZZA HD Chorea Patient Brochure

Ready to take HD chorea control a step forward?

The Doctor Discussion Guide has tips for talking to a healthcare provider about your uncontrollable movements and HD chorea treatment options.

Download Guide
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INGREZZA takes HD chorea control a step forward

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INGREZZA offers simple dosing that’s always one capsule, once daily

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